The news is filled with stories about Ebola, and breast cancer gets a lot of press too. Would it surprise you to know that neither makes the list of the 10 deadliest diseases? Even more surprising, perhaps, is that several of the deadliest diseases, including the number one killer in the world, are at least partially preventable. Where a person lives, access to preventive care, and quality of healthcare all factor into their risk.
The top five deadliest diseases haven’t changed much in the past decade, but we’ve managed to lower the number of deaths for some of the top 10 deadliest diseases.

1. Coronary Artery Disease (Ischemic Heart Disease)

The deadliest disease in the world is coronary artery disease (CAD). CAD, also called ischemic heart disease, occurs when the blood vessels that supply blood to the heart become narrowed. The World Health Organization (WHO) estimates that about 7.4 million people died of ischemic heart disease in 2012. That was about 13.2 percent of all deaths.
In the United States, about 600,000 people die of heart disease every year, according to the Centers for Disease Control and Prevention (CDC). That makes it the deadliest disease in the U.S., as well as the world. In the U.S. the most common type of heart disease is CAD, which takes about 380,000 lives each year.
Among the risk factors are high blood pressure, high cholesterol, and smoking. Regular exercise, good nutrition, and weight control can help lower your risk of developing CAD.
Where you live matters. Although it’s still the leading cause of death, mortality rates have declined in many European countries and in the United States. This may be due to better prevention and access to quality healthcare. However, in many developing nations, mortality rates due to CAD are on the rise.